Sara Howard previously employed as the personal assistant to New York Police Commissioner Theodore Roosevelt, has used that experience and her participation in the Beecham case (season one) to set up the Howard Detective Agency, acting as a private detective primarily for cases brought by women. Self-possessed and intelligent, well-bred and well-spoken, fearless and adept with a gun, she invites Dr. Kreizler and John Moore to join her once again as she works to rescue the kidnapped infant daughter of a Spanish diplomat from a dangerous killer.